{"id":1952,"date":"2024-04-04T13:26:14","date_gmt":"2024-04-04T13:26:14","guid":{"rendered":"https:\/\/stoxpo.com\/?p=1952"},"modified":"2024-04-04T13:26:15","modified_gmt":"2024-04-04T13:26:15","slug":"candel-therapeutics-reports-encouraging-survival-data-for-can-2409-in-pancreatic-cancer","status":"publish","type":"post","link":"https:\/\/stoxpo.com\/index.php\/2024\/04\/04\/candel-therapeutics-reports-encouraging-survival-data-for-can-2409-in-pancreatic-cancer\/","title":{"rendered":"Candel Therapeutics Reports Encouraging Survival Data for CAN-2409 in Pancreatic Cancer"},"content":{"rendered":"\n

Updated Interim Results Show Prolonged Survival and Immune Activation in Borderline Resectable PDAC Patients<\/h4>\n\n\n\n

Candel Therapeutics (CADL), a clinical-stage biopharmaceutical company focused on innovative cancer immunotherapies, unveiled promising interim survival data from its ongoing phase 2 trial of CAN-2409 for pancreatic ductal adenocarcinoma (PDAC). The updated findings, presented by Chief Medical Officer Garrett Nichols, MD, MS, at the 2024 data cut-off, showcase significant improvements in overall survival and immune activation.<\/p>\n\n\n\n

Patients treated with CAN-2409 plus valacyclovir, alongside standard chemoradiation, exhibited a median overall survival of 28.8 months, compared to 12.5 months in the control group. Notably, survival rates at 24 and 36 months were substantially higher in the CAN-2409 cohort, indicating durable benefits.<\/p>\n\n\n\n

Furthermore, analyses of resected tumors revealed dense aggregates of immune cells, suggestive of robust antitumoral immune responses. The treatment’s safety profile remained favorable, with no dose-limiting toxicities observed.<\/p>\n\n\n\n

Paul Peter Tak, MD, PhD, President and CEO of Candel, expressed optimism about CAN-2409’s potential to reshape the pancreatic cancer treatment landscape by modulating the tumor microenvironment and enhancing immune responses. These findings underscore the promise of CAN-2409 as a transformative therapy for patients with PDAC.<\/p>\n\n\n\n

Read original press release:here<\/mark><\/a><\/p>\n\n\n\n

You might like this article:Tesla Explores India for $2-3 Billion Electric Car Plant<\/mark><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Updated Interim Results Show Prolonged Survival and Immune Activation in Borderline Resectable PDAC Patients Candel Therapeutics (CADL), a clinical-stage biopharmaceutical company focused on innovative cancer immunotherapies, unveiled promising interim survival data from its ongoing phase 2 trial of CAN-2409 for pancreatic ductal adenocarcinoma (PDAC). The updated findings, presented by Chief Medical Officer Garrett Nichols, MD, […]<\/p>\n","protected":false},"author":1,"featured_media":1424,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","jnews-multi-image_gallery":[],"jnews_single_post":{"subtitle":"","format":"standard","video":"","gallery":"","source_name":"","source_url":"","via_name":"","via_url":"","override_template":"0","override":[{"template":"8","single_blog_custom":"","parallax":"1","fullscreen":"1","layout":"right-sidebar-narrow","sidebar":"author","second_sidebar":"single-right","sticky_sidebar":"1","share_position":"top","share_float_style":"share-monocrhome","show_share_counter":"0","show_view_counter":"0","show_featured":"1","show_post_meta":"1","show_post_author":"1","show_post_author_image":"1","show_post_date":"1","post_date_format":"default","post_date_format_custom":"Y\/m\/d","show_post_category":"1","show_post_reading_time":"1","post_reading_time_wpm":"300","show_zoom_button":"0","zoom_button_out_step":"2","zoom_button_in_step":"3","show_post_tag":"1","show_prev_next_post":"1","show_popup_post":"1","number_popup_post":"1","show_author_box":"1","show_post_related":"1","show_inline_post_related":"0"}],"override_image_size":"0","image_override":[{"single_post_thumbnail_size":"crop-500","single_post_gallery_size":"crop-500"}],"trending_post":"0","trending_post_position":"meta","trending_post_label":"Trending","sponsored_post":"0","sponsored_post_label":"Sponsored by","sponsored_post_name":"","sponsored_post_url":"","sponsored_post_logo_enable":"0","sponsored_post_logo":"","sponsored_post_desc":"","disable_ad":"0"},"jnews_primary_category":{"id":"","hide":""},"jnews_social_meta":{"fb_title":"","fb_description":"","fb_image":"","twitter_title":"","twitter_description":"","twitter_image":""},"jnews_override_counter":{"override_view_counter":"0","view_counter_number":"0","override_share_counter":"0","share_counter_number":"0","override_like_counter":"0","like_counter_number":"0","override_dislike_counter":"0","dislike_counter_number":"0"},"jnews_post_split":{"enable_post_split":"0","post_split":[{"template":"1","tag":"h2","numbering":"asc","mode":"normal","first":"0","enable_toc":"0","toc_type":"normal"}]}},"categories":[308,358],"tags":[],"coauthors":[453],"_links":{"self":[{"href":"https:\/\/stoxpo.com\/index.php\/wp-json\/wp\/v2\/posts\/1952"}],"collection":[{"href":"https:\/\/stoxpo.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/stoxpo.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/stoxpo.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/stoxpo.com\/index.php\/wp-json\/wp\/v2\/comments?post=1952"}],"version-history":[{"count":1,"href":"https:\/\/stoxpo.com\/index.php\/wp-json\/wp\/v2\/posts\/1952\/revisions"}],"predecessor-version":[{"id":1953,"href":"https:\/\/stoxpo.com\/index.php\/wp-json\/wp\/v2\/posts\/1952\/revisions\/1953"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/stoxpo.com\/index.php\/wp-json\/wp\/v2\/media\/1424"}],"wp:attachment":[{"href":"https:\/\/stoxpo.com\/index.php\/wp-json\/wp\/v2\/media?parent=1952"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stoxpo.com\/index.php\/wp-json\/wp\/v2\/categories?post=1952"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stoxpo.com\/index.php\/wp-json\/wp\/v2\/tags?post=1952"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/stoxpo.com\/index.php\/wp-json\/wp\/v2\/coauthors?post=1952"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}